Alexandrov Team

Spatial Lipid Fluxes

The is an art for the 13C-SpaceM method publication selected for a cover of Nature Metabolism. It is a photo of a cross-stitch embroidery with a part of the imaging mass spectrometry heatmap used as a scheme. Loose threads outside of the hoop symbolize the metabolic fluxes studied in this project.

Authors	Alyona Buglakova (EMBL)
Date	2024

Read paper on 13C-SpaceM in Nature Metabolism

SpaceM

This is an art piece prepared by the graphical artist Veronique Rappez. It conceptulally represents a cell with small molecules as its constituents, with laser ablating a part of the cell.

Authors	Veronique Rappez
Date	2021

Read paper on SpaceM in Nature Methods

Revealed Metabolism

The image shows, in artistic way, the intracellular intensities of oleic acid in hepatocytes. On the left it shows microscopy images of the cells. On the right it overlays the intensities of the oleic acid.

Authors	Theodore Alexandrov, Luca Rappez (EMBL)
Date	2018

Read paper on SpaceM in Nature Methods

Woman & Man

This image shows localization of small molecules on two individuals, as mapped by 3D molecular cartography (see Projects), visualizing data from Bouslimani et al, 2015. Originally, his image was prepared for the ISMB'2013 art & science competition. Later on, it was updated overlaying cell images from a single-cell metabolomics study. The image was selected as an Image of the Year by Nature in 2015 and as a Biomedical Picture of the Day by MRC London Institute of Medical Sciences in 2018.

Authors	Theodore Alexandrov (UCSD, EMBL)
Date	2013, 2018

Read paper in PNAS

Starry Night of Cells

This image was prepared as a cover image for a PhD students symposium at EMBL. Alyona was a graduate student in our team at the time and she was inspired by microscopy images of single cells which we acquire for single-cell metabolomics.

Authors	Marina Makharova, Alyona Buglakova (EMBL)
Date	2021